William F. Koch, Ph. D., M. D.

Generic selectors
Exact matches only
Search in title
Search in content
Search in posts
Search in pages


Copyright 1941 by D. H. ARNOTT, MD.


The most potent forces affording us protection from disease are natural within our bodies. These functionings are inherited; and where our ancestors constantly have survived particular diseases, selective resistance to these troubles frequently has been passed on to us. Therefore, heredity is in no wise a thing apart from the environment of our predecessors. To understand many difficult medical problems of today, one must never lose sight of this fact.

For good health, a supply of food adequate in amount and variety must be used; but there is another requisite for good health-one which is clear to, and frequently under the control of those physicians who treat their patients by using the catalytic agents discovered and developed by Dr. Wm. F. Koch, of Detroit, Michigan.

This further needed condition requires that the body transform food into living energy at a vigorous normal rate, burning it properly in each individual cell in the body, where it continuously unites with oxygen for this purpose.

It is upon the degree approaching perfection with which this is done consistently, the fundamental conditions requisite for the best of good health depend.

Therefore, when there has been established a long-continued. sluggish habit of this fundamental, biochemical reaction, various pathological states must and do arise from this one cause.[1]

It is Dr. Koch’s belief that the last step in the transition of energy contained in the food we consume for nourishment, into that of living energy-life as we see it-takes place through the catalytic action of certain carbon compounds which are natural to the body; and that a chronic deficiency of oxidation necessary for vigorous living energy and requisite for its support, results when the supply of these essential compounds becomes depleted.

He believes this deficiency frequently can be corrected by the hypodermic administration of the solutions which he discovered and has developed, and which-named Glyoxylide-he distributes to doctors in single glass ampules, together with hypodermic syringe and needle, all sterile and ready for use and which must be used as received.

In writing of the Koch treatment, one of the highest ranking scientists in Europe[2] who had “spent the last five years in the study and development of this treatment” reaffirmed his opinion expressed previously:


From a long list available, let us examine two important, distinctive, easily-repeatable, clinical successes obtained through the administration of the Koch treatment, which together place this statement beyond dispute.


[4] “Miss A. R.

PRESENT COMPLAINT: The left foot had been badly discolored for some months, was stone cold to the touch and devoid of feeling.

PHYSICAL FINDINGS: The left foot was black, cold to the touch, and for a distance of nine inches up the leg the colour of the skin was dark red, mottled with several darker patches. It was evident that there was a serious degree of obliterative endarteritis affecting these parts.

TREATMENT: One cc. of Glyoxylide was given immediately. (February 7th, 1938)

SUBSEQUENT HISTORY: Observed thirty hours after the treatment was given the whole foot was dark red in colour the day following it was pink and white. Ten days later it was normal in appearance and warm to the touch. The patient at this time reported that the foot felt warm to her. Later on she could walk with the normal tactile sense restored. At the time of writing, April 18, 1939, the foot is normal in appearance and the patient reports no abnormal feelings or disabilities exist in the affected parts. Also, she says that her general health has improved so that it is better than it had been for several years previously…

DR. KOCH’S treatment rests upon the theory that his reagents are directed towards a defective oxidative mechanism in order to restore this function to its normal efficiency. The condition in the patient described illustrates a gross and unmistakable defect in oxidative mechanism of the left foot and the lower part of the left leg. The restoration of a normal oxidative function after the use of Glyoxylide was prompt, readily recognized, and by the use of one dose of Glyoxylide re-established as a continuing habit.”

This patient continues well at the time of writing, November 15th, 1941.

For more than 50 years post mortem findings have disclosed Obliterative Endarteritis, such as affected the foot of Miss A. R., has its parallel in the pathology exhibited in Coronary Thrombosis.

[5] ” Dr. H. G. A.-Age 64.

A physician, like our father before us, had been bothered for a couple of years with pain and stiffness in his shoulder joints; but one did not recognize the essential rheumatic nature of his disability. While walking down Yonge St., Toronto, December 2, 1936, he was suddenly disturbed with a severe pain in the center of his chest. After resting a short time, this passed away. However, it returned with terrible severity two days later, while he was quiet in his own home. Heavy, hypodermically-administered doses of morphine relieved him, only while the narcotic action rendered him unconscious.

W. M., noted on page 128 of ” Natural Immunity,” still was alive and well, so Glyoxylide was used December 8, and this gave him considerable relief in a few hours. Three and a half days later, a second dose was given, following which all pain subsided and has not recurred.

Five weeks after the pain had left him, an electrocardiogram showed evidences of severe coronary damage. Nine weeks later, a second tracing disclosed a practically normal condition. These graphs are reproduced. (Omitted here).

The injury to his vitality has been most far reaching and the first ten weeks of convalescence were spent in bed, for the most part. But, long before he was able to be around, he was surprised and pleased to find himself free from his stiff, sore shoulder symptoms.

For a time I had observed his lips were pale or cyanosed when he had become fatigued, but soon after the Glyoxylide was used, this gave place to a normal healthy appearance.

Now, fourteen months since his seizure, he leads a normal, fairly active life, free from any sign of his old coronary symptoms.”

Nearly five years later, November 15th, 1941, he is active and well.


For some time previous to being struck down myself by a severe and commanding attack of Coronary Thrombosis on November 12th, 1940, had been well aware from repeated slight seizures of what impended. During 1938-39-40, I had been constantly engaged in, and deeply preoccupied with preparing and assisting to present the Cancer Commission of the Province of Ontario with adequate information and substantial proof of the merits of the Koch treatment.[6]

In July of that year a situation had developed, serious enough to warrant the Department of the Attorney-General in showing considerable concern. Interviews with me solicited by the Department were granted, and the documentary evidence which the Department expressed a desire to possess was placed in its hands. Therefore, I was reluctant to admit to myself, or to disclose to anyone this threat to my health and life, lest the Department might regard their chances for successful action in the public interest were lessened thereby. The deliberate delay in caring for myself properly, enabled me to prevent any such consideration entering into the picture.


Pain is a term we apply to suffering which may be slight or severe. This is so with the pain of coronary disease; but the pain is of a grinding-pressure type located in the mid-sternal region.

The character and location of the pain in coronary disease is rather distinctive, and first is experienced during exercise or emotion sufficient to raise the frequency of the heart beat. After lying down, relief from the pain comes with disquieting delay. The pain may continue for hours and may recur, unprovoked by exercise or emotion.

Pain, as described above, experienced by a patient from the early forties on, otherwise unexplained, is a strong indication of coronary disease.

Some seizures may add to the essential clinical picture by giving the history of pain also extending up the neck, and into the jaws, or down one or both arms, during seizures.

Now that in the Koch treatment of coronary thrombosis we have an easily applied, and highly successful active medicinal treatment of the disease, negative findings by an electrocardiograph examination in the face of symptoms described above, unless accompanied by a written and signed definite alternative diagnosis by the cardiologist, should not be allowed to carry even the most trivial weight. Only too frequently has the electrocardiograph finding been negative where the disease subsequently, in a matter of weeks, caused the death of the patient.

After a firm diagnosis has been obtained, the Koch treatment can be used by the general practitioner with confidence that the suffering can be controlled; and the pathological trend reversed; and the patent restored to gainful pursuits, in over 90 % of those properly treated.


The program of treatment should be outlined for the patient and agreed to by him before direction of the case is assumed. The patient should agree to re main in his room continuously for six to eight weeks, except where the bathroom is on the same floor and close to hand. Daily enemas should be used and a bland diet chosen from the general diet list approved by Dr. Koch.

The active medicinal treatment consists of the subcutaneous or intramuscular hypodermic administration of Koch’s Glyoxylide[7] in doses of 2 c. c. This is sharply painful for two or three minutes. but it soon passes and no local inflammation results. Being made from pure chemicals it is entirely free from the hazards inherent to the therapeutic inoculation of serums, tissue extracts or bacterial vaccines.

The interested physician will learn from his patients how far-reaching has been the constitutional upset. Early in the attack food of any kind often is disturbing. When this is so, I recommend that the noon meal be eliminated entirely, during this period. The enemas, though effectual, may give no convincing sense of evacuation to the patient. There may be times, and hours, when some return of pain is reported, but it will be found to be less severe and to subside more quickly as the weeks pass.

While confined to his room, the patient should not be required to remain in bed continuously, but should be allowed to sit up, resting his arms and head on a pillow placed on a table suitable for that purpose, or in any other position he finds most comfortable.

The reversal of the pathological trend effected by the use of the Koch treatment should have six to eight weeks to make progress before any exercise be allowed the patient beyond the limited confines agreed upon. Then the patient should be instructed to exercise carefully, resting as soon as any definite symptom of pressure in the mid-sternal region has been provoked by it.

In my own problem the recovery has progressed nearly at the same pace which characterized. the onset of the symptoms. It was eight hours after the treatment was injected before satisfactory comfort resulted. Since that time some definite improvement has been noted each month for a year now. This was instituted and has been held by the use of but one dose of Glyoxylide.

Where recurring symptoms disturb the patient treated for coronary thrombosis, I think Glyoxylide could be repeated with benefit at three-month intervals.

These patients should be taught to practice deep breathing. They should inhale as deeply as possible and exhale thoroughly in a group of ten to twenty respiratory excursions every hour. This should be done while lying or reclining comfortably, and may provide the tissues with extra oxygen needed by the treatment; and often will prove effective in cutting short a return of symptoms.

An attack of influenza should cause the gravest concern, and Glyoxylide should be repeated as a rule, four to six weeks after convalescence has been established.

No set of rules can be drawn up which shall prove to be both simple and practical, and for which no exceptions shall occur. When graduated exercises can and should be used, usually depends upon the length of time the pathology existed prior to using the Koch treatment; the general severity of the attack; and the age of the patient. In the mildest type of seizure this should be delayed for six weeks after using the Koch treatment; and in the more severe, as much as twice that time.

With the reversal of the pathological trend well established, graduated controlled exercise to the point of return of slight discomfort can and should be instituted. In this way, there can be a period of careful, constant and useful conditioning aimed towards eventually meeting ordinary demands. Symptoms of discomfort can be countered effectively by resting, accompanied by deep breathing.

Those physicians who went through the Influenza Epidemic which began in 1918, had plenty of opportunity to become infected with a strain of virus which to them was of particular virulence. It is quite possible that we now know why Coronary Thrombosis so aptly has been termed “the doctors’ disease.”

In reviewing my own clinical experiences, I think I have been able to recognize two types of Influenza seizures which were most liable to be followed by Coronary Disease:

One is characterized by the severe and prolonged acute stage of the attack; the other resembled a slight cold, produced no prostration, but ran a course of many months, during which exacerbations for a few days, disclosed the failure to establish immunity to the disease. I believe my own attack of Coronary Thrombosis had, its origin in a seizure of this type.

Largely, natural immunity is a matter of inheritance. In our own civilization there had been no opportunity for selective immunity to have been acquired in this way as a protection against the ravages of the Influenza Epidemic of 1918, and subsequent years. The present high mortality from Coronary Thrombosis might well be some of the far-on consequences of that disease.

It is not intended here to recount any of the various cogent reasons for this view.

[8] Elsewhere I have made record of the usefulness of the Koch Glyoxylide. These published clinical reports have been repeated and have been fully corroborated by other[9] “medical men whose scholarship and practical experience with the treatment proved them well qualified for the work.”

Those suffering from Coronary Thrombosis can have their condition correctly diagnosed by the General Practitioner. He also can use the Koch treatment so effectively that 90% thereby could have restored to them an important measure of dependable good health.


To disclose the nature of the Koch treatment; how it acts naturally and effectively; how to apply it successfully in the pathological states described above, is regarded as sufficient justification for the publication of this brief brochure.

No academician so prominent or scornful as to shake our faith! No dialectician so facetious and impudent as to disturb our conviction! What we have learned through using the Koch treatment during many years, we know. Ours is a living knowledge: It has grown; it continues to grow.


[1] “Pathogenesis and Immunity, As Conveyed by Ethylene and Carbonyl Groups.-In the Cause and Cure of Cancer, Allergy and Infection.”

[2] “Proceedings”: Cancer Commission, Province of Ontario, Canada, regarding Koch treatment, 1938-39440-D. H. A Arnott, M.D., page 366. Price one dollar, Koch Laboratories.

[3] “Proceedings”: Page 45.

[4] “Proceedings”: Pages 51-52.

[5] “Reversing the Pathological Trend in Rheumatic Fever and Coronary Thrombosis.”

[6] “Proceedings”: Cancer Commission, Province of Ontario, Canada, regarding Koch treatment, 1938-39-40-D. H. A. Arnott, M.D.

[7] “Pathogenesis and Immunity,” as conveyed by Ethylene and Carbonyl Groups.

[8] “Reversing the Pathological Trend in Rheumatic Fever and Coronary Thrombosis.”

[9] “Proceedings”: Cancer Commission, Province of Ontario, Canada, regarding Koch treatment, 1938-39-40-D. H. A. Arnott, M.D.